

CrioSix Cryoultrasound Therapy:
Advanced Cold & Ultrasound Treatment for Pain Relief and Recovery
The CrioSix Cryoultrasound combines of cryo and sound waves into one cryo therapy device. Furthermore CrioSix is widely trusted by athletes and clinicians. CrioSix successfully targets muscle injuries and penetrates deep into connective tissue layers. Consequently this speeds up healing and recovery. With this clinically proven focussed cooling technology, CrioSix therapy device is a unique device.
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What is CrioSix Cryoultrasound Therapy?
Cryotherapy = pain relief and inflammatory reduction
Ultrasound = enhanced injury recovery through growth factor promotion
Speed of recovery in Athletes resulting from cryo therapy, is the primary factor that contributed to its’ success in the sporting world. Cyro-US therapy has since made its way into traditional methods of treatment (Vulpiani et al., 2015).

How Does Cryoultrasound Work?
Cryo-US Therapy: Enhancing Recovery with Cooling and Ultrasound
Cryo-US therapy successfully combines focused cooling with therapeutic sound waves, therefore offering a sophisticated solution for reducing edema, easing pain, and facilitating recovery. Moreover as a key component of modern injury treatment, cryotherapy efficiently controls swelling and alleviates discomfort.
Utilising ultrasound to emit high-frequency oscillatory sound waves, CrioSix has a gentle peak pressure of 0.5 bar. This method is less intense than shock wave therapy, ensuring a milder approach.
Dual-Action Benefits of Cryo-US Therapy:
- Enhances Blood Flow and Muscle Relaxation: generates internal heat that increases blood circulation and relaxes muscles.
- Boosts Collagen Flexibility: triggers a pro-inflammatory response that speeds up recovery.
- Stimulates Tissue Regeneration: Utilizing non-thermal effects such as ultrasonic cavitation and microstreaming, CrioSix promotes fibroblast activity, protein synthesis, and tissue regeneration. Additionally it enhances blood flow and supports bone healing.
Clinicians, physiotherapists, and sports therapists trust Cryo-US Therapy for its effectiveness in targeting deep tissue layers and optimising recovery outcomes. Consequently Cryo US is renowned for its precision and ability to improve healing processes, making it a preferred choice in therapeutic settings.
Key Features of the Cryo Ultrasound Action
CrioSix combines cold and ultrasound treatments to reduce pain, inflammation, and edema. In fact cold therapy suppresses pain receptors and restricts blood flow, controlling edema and providing pain relief. Simultaneously CrioSix generates high-frequency sound vibrations that produce mechanical, thermal, chemical, and cavitation effects, aiding in tissue healing and reducing inflammation. US also improves vascularisation and removes inflammatory molecules. The combination of these therapies provides deep micromassage and a calming effect on damaged tissues (Paoloni et al., 2015).

What can Cryoultrasound Therapy Achieve?
- MUSCLE RECOVERY
- IMPROVED SLEEPING
- CHRONIC PAIN RELIEF
Cryotherapy is commonly used to accelerate the healing of muscles and tissues after physical activity or injury. Fundamentally this is based on the physiological changes that occur in the body in response to exposure to cold and hot temperatures.
Understanding the Body's Response to Cold and the Benefits of Cryo-US Therapy
When exposed to cooler temperatures, your body begins a process known as vasoconstriction. This narrows the blood vessels, redirecting blood flow towards vital organs and enriching the blood with oxygen and nutrients. In turn as your body returns to warmth, vasodilation occurs. Because of this the blood vessels broaden, allowing oxygen-rich blood to flow back to the tissues. Consequently this process helps eliminate inflammation and toxins, which aids in recovery.
Cryo-US therapy successfully reduces chronic pain....
By decelerating nerve impulse transmissions, a well-documented effect of cold exposure. Additionally, cryotherapy has been shown to enhance sleep quality by reducing muscle inflammation and damage. Finally it also stimulates the sympathetic nervous system, which plays a crucial role in regulating sleep.
Cryo in action
CrioSix is used by a large number of sporting teams and premium clinics around the world.
“Instant relief for the patient great for rebookings”
September 2023
CRYO THERAPY CLINICAL STUDIES?
1. Vulpiani et al. (2015) and Vural et al. (2014) found that cryo-ultrasound therapy effectively combines therapeutic ultrasound and cryotherapy, improving recovery and pain relief.

2. Costantino et al. (2014) found that cryo-ultrasound therapy is effective for treating persistent plantar fasciitis, providing long-lasting pain relief and improved function.
3. Liu et al. (2019), evaluated cryo-ultrasound therapy for its effectiveness in treating chronic shoulder tendinopathy.
4. Smith et al. (2018) conducted a randomized controlled trial on patients with knee osteoarthritis to assess the effectiveness of cryo-ultrasound therapy.
230 V, 50 Hz
1 MHz ultrasound source – Quartz foil
Maximum effective intensity – 3 Watt x cm2
Continuous – Pulsed – Intermittent
Square wave
50 HZ
3 Sec action and 2 Sec pause
7 cm2 / 4.9 cm2
Maximum effective intensity – 2.5 Watt x cm2
Up to -8 ° C
48 × 36 x 117h cm
Approximately 75 kg
Applied standards The design of the medical device took place using the applicable technical standards.